Woman sleeping using the cannula alternative for oxygen therapy the Oxyllow System for side sleepers.

Return to a good night's sleep.

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Top view of Oxyllow System without a pillow. Shows the tubing connection with diffuser heads.

The cannula-free solution for a restful night.

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A good nights rest after using the Oxyllow System for oxygen therapy.

Take back the night with the Oxyllow® System

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Close up on Oxyllow system in the background after getting a good nights sleep.

Take back the night with the Oxyllow Pillow.

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Close up on the Oxyllow System, the nasal cannula alternative for oxygen therapy.

The cannula-free solution for a restful night.

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Close up on a side sleeper using the Oxyllow System to get comfortable oxygen therapy.

Return to a good night's sleep.

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Side sleeper using the Oxyllow System, Side view of the Oxyllow System

Introducing the Oxyllow® System, the only cannula-free oxygen therapy solution for those who suffer from respiratory conditions.

This revolutionary FDA-Registered device delivers a cannula-free sleep. Its unique, ergonomic design promotes easy breathing, freedom of movement, and a return to a more restful sleep.

The fact is, over 1.5M patients need oxygen therapy at night. The standard devices currently available make sleeping with oxygen concentrators uncomfortable, causing potential nose bleeds, skin cracking, entanglement with cannulas and tubes, and skin irritation around the nose and ears. Even worse, the effects of a restless or sleepless night can lead to depression, hypertension, and strokes.

There is a better way to deliver the flow of oxygen without disrupting your sleep.

The Oxyllow® System is the “no-wear” solution to night time oxygen. The Oxyllow® Oxygen System connects seamlessly with your stationary oxygen concentrator source to form an oxygen-rich pocket while lying on your pillow without disrupting the continuous flow of oxygen. It caters specifically to side and stomach sleepers, reducing the need to struggle with tubes and equipment. The result is a more comfortable, soothing night’s rest, and an effective alternative to cannulas.

Lady opening her window. It looks as if she has just gotten out of bed.

We believe in empowering oxygen dependent patients to regain freedom and quality of sleep.

Nurse and patient smiling and giving a thumb up.

10 out of 10 patients said that the product was intuitive to put together and use.

Cartoon image that shows how the Oxyllow System goes on the pillow for a side sleeper.


Experience greater comfort with this revolutionary design – an oxygen-rich environment thoughtfully positioned on both sides of your face. This ingenious feature eliminates the necessity for cumbersome cannulas.

Side sleeper cartoon using the Oxyllow System.


Embrace the freedom of untethered sleep. Say farewell to tubes on your face as you enjoy the convenience of effortless movement from side to side. This innovative solution liberates you from the struggle of managing a steady flow of oxygen delivery during the night, offering a seamless and unburdened slumber experience.

Cartoon image that shows how the Oxyllow System goes on the pillow for a side sleeper.


Think of this as personalized comfort. Tailor your oxygen delivery exactly where you desire it on the pillow, letting you be in control of your oxygen delivery experience. This unique feature enhances your comfort and ensures optimal oxygen distribution, allowing you to revel in a sleep environment fashioned to your needs.

100% Payment and Data Secure

We have your back. We do not collect or share your data with others.

30 Day Return

Give it a chance, and if, after 7 days you are still unsatisfied or the product does not work for you, we will refund your payment in full, minus shipping costs

Support 24/7

Satisfaction guaranteed. Reach out to 574-367-6552 with questions or concerns

Take back the night with the Oxyllow® System